Profile of andarine s4

Andarine, known as S4, belongs to the early group of SARMs delivering higher muscle mass and lower body fat alongside strength gains. This yields a dense and defined physique, valued during cutting cycles.

Compared to other SARMs, S4 causes milder suppression of natural testosterone while keeping high potency. Vision changes during use remain a known and reversible side effect. The compound also shows potential protection for the prostate.

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Understanding andarine s4

S4 (Andarine) was created by GTx to show anabolic activity in tests. Human trials stopped due to visual side effects like yellow tint and low night vision, which fade rapidly after stopping use.

Although unmarketed as medicine, andarine sees use in fat loss and body shaping like Ostarine. In strength and hormone suppression, S4 sits between Ostarine and LGD-4033, exceeding Ostarine while trailing LGD.

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Laboratory findings

Animal tests spanning up to 120 days demonstrated that andarine (S4) performs the following actions:

• builds skeletal muscle mass

• elevates physical strength

• cuts body fat

• raises bone mineral density

A potential effect of preventing bone resorption has also been observed, making S4 interesting for skeletal health as well.

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Core actions of andarine s4

• Muscle Mass Gain: supports lean tissue growth

• Strength Increase: users note gym performance gains

• Fat Reduction: fits the cutting phase

• Bone Density Rise

• Prostate Defense: S4 binds partial receptors in the prostate, blocking DHT action without triggering growth

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Hormone level suppression

Like all SARMs, andarine suppresses the body’s natural production of testosterone. However, S4 It appears to be less suppressive than compounds such as LGD-4033 or RAD-140.
To limit the hormonal impact, many users also take:

• SERMs such as clomiphene or tamoxifen

• testosterone or gonadotropin during the cycle

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Liver and lipid impact

No significant increases in liver enzymes have been reported with S4, but high doses may increase the risk of side effects.
Like other SARMs, andarine may affect the lipid profile: the

• HDL cholesterol drops

• LDL cholesterol rises

Blood tests prove necessary during cycles.

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Vision changes

One of the most well-known side effects of S4 It is a temporary disturbance of vision:

• yellowish tint

• low night vision

• slow light adaptation

These dose-linked reactions fade quickly upon stopping. Lowering the dose helps if they arise.

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Active half-life

• 4–6 hours

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Usage amounts for andarine s4

• Beginner level: 20 mg

• Standard dose: 25–75 mg

• Top limit advice: 100 mg

• Female users: 10–20 mg